Published studies funded by Invest in ME Research and supported by our fundraising for the charity

Searching for Serum Antibodies to Neuronal Proteins in Patients With Myalgic Encephalopathy/Chronic Fatigue Syndrome
Authors: Giannoccaro MP,  Cossins, Sørland, Fluge Ø, Vincent A
May 2019, Clinical Therapeutics
(ProfessorAngela Vincent is involved in ME research as a scientific advisor to IiMER. Funding from the charity was not required for this work).

A role for a leaky gut and the intestinal microbiota in the pathophysiology of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Author: Daniel Vipond, Doctoral thesis,
April 2019, University of East Anglia

CD24 Expression and B Cell Maturation Shows a Novel Link With Energy Metabolism: Potential Implications for Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Authors: Fane F. K. Mensah, Christopher W. Armstrong, Venkat Reddy, Amolak S. Bansal, Saul Berkovitz, Maria J. Leandro, Geraldine Cambridge
October 2018, Frontiers in Immunology

Does the microbiome and virome contribute to myalgic encephalomyelitis/chronic fatigue syndrome?
Authors: Fiona Newberry, Shen-Yuan Hsieh,  Tom Wileman,  Simon R. Carding
March 2018, Clinical Science

Chronic fatigue syndrome and the immune system: Where are we now?
Authors: Fane Kojo Fosu Mensah, Amolak Singh Bansal, Brian Ford, Geraldine Cambridge
April 2017, Neurophysiologie Clinique/Clinical Neurophysiology

A Role for the Intestinal Microbiota and Virome in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)?
Authors: Navena Navaneetharaja, Verity Griffiths, Tom Wileman, Simon R. Carding 
June 2016, Journal of Clinical Medicine

Extended B cell phenotype in patients with myalgic encephalomyelitis/chronic fatigue syndrome: a cross-sectional study.
Authors: F. Mensah, A. Bansal, S. Berkovitz, A. Sharma, V. Reddy, M. J. Leandro, G. Cambridge
December 2015, Clinical & Experimental Immunology

Dysbiosis of the gut microbiota in disease
Authors: Simon Carding, Kristin Verbeke, Daniel T. Vipond, Bernard M. Corfe & Lauren J. Owen
(No funding was required for this article and it is not ME-specific but IiMER-funded PhD candidate Daniel Vipond is one of the authors.)
February 2015, Microbial Ecology in Health and Disease
DOI: 10.3402/mehd.v26.26191

Blogs and Articles by the Researchers

“Metabolomics And B Cell Metabolism: Pointing The Way To Understanding Disturbed Immune Function In Patients With ME/CFS)”
Update by Jo Cambridge on IiMER-funded research at UCL, August 2018

“Defining autoimmune aspects of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)”
Update by Katharine Seton on her IiMER-funded study at QI, February 2018

“Defining autoimmune aspects of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)”
Introduction by Katharine Seton on her IiMER-funded study at QI, November 2017

News by Fane Mensah (funded by IiMER for B-cell research at UCL) of collaboration with Christopher Armstrong of Melbourne University, supported by Solve ME/CFS (initiated at 2016 Invest in ME London Conference) and of the work of a student in the research supported by IiMER, February 2017

Do the Answers to ME/CFS lie within our Gut?
Article by Ben Halford on detailed literature review led by IiMER-funded medical students Navena Navaneetharaja and Verity Griffiths at QI, July 2016 (Naveena’s own blog link is broken as it was posted on IFR blog before transitioning to QI so here is an extract we quoted at the time):

“Our recent review highlights current understanding of the role of infection in triggering myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). We focus on the origin of persistent immune-related symptoms in the condition and describe mechanisms that may explain underlying immune impairment and potential autoimmune processes in ME/CFS, where B cell depletion therapy is of significant therapeutic benefit. We also provide focus for further research by exploring the potential impact of the intestinal microbiome and virome using sensitive study designs.”

“The next steps in the Carding lab are to correlate phage populations in patients with severe disease compared to house-matched controls. This work has the potential to elucidate more distinct subpopulations within current ME/CFS classifications and of upmost importance, has the potential to influence therapeutics, providing much-needed approaches in preventing and managing a disease in need of confronting.”

ME/CFS – Through The Eyes of a Young Researcher
Introduction by Fane Mensah to his IiMER-funded work at UCL, January 2015

All Invest in ME Research Blogs

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to help this work continue until diagnostic tests and medical treatment options are established for M.E.