£200k target hit for IiMER Gut Microbiota Fund!

You’ve done it again!

We are pleased to announce that another target for our crowdfunding campaign for a strategy of biomedical research into ME has been reached.

This update to our gut microbiota and related projects fund being performed at the UK Centre of Excellence for ME hub in Norwich Research Park brings the total raised so far for projects there to £200,000.

The research found, funded and facilitated by Invest in ME Research is the result of dedicated, generous and determined supporters who have not just given money but, also huge amounts of time and effort toward helping us change the direction of research into ME in UK and Europe.

The latest target has allowed us to fund two PhD studentships currently undertaking research at the Centre of Excellence hub in Norwich Research Park and allowed us to decide to commit to the future funding of another PhD at the Centre.

Please click here for the full update by Invest in ME Research giving details of the latest study in the biomedical research programme and other projects related to the UK Centre of Excellence for ME, and a message to you from the charity’s Chairman Kathleen McCall: http://www.investinme.org/ce-news-1709-04.shtml

We supporters at Let’s Do It for ME would like to thank the Trustees and Scientific Advisory Board of Invest in ME Research for their vision and dedication, and everyone working with them to establish diagnostic tests and medical treatment options for some 250,000 people with ME in UK and millions around the world.

Our thanks to each and every individual, family, group, team, organisation or company contributing to this vital research and supporting by whatever means.

Let’s keep doing it for ME!

We now have a fundraising page on BT MyDonate: https://mydonate.bt.com/fundraisers/fundraising4me1

£520k target hit for IiME Research Rituximab Fund!

You did it for ME! Let’s keep doing it! We supporters at Let’s Do It for ME would like to thank each and every individual, family, group, team, organisation or company contributing to this vital research and supporting by whatever means.

We would of course, also like to thank the forward-thinking and incredibly hard-working Trustees and Scientific Advisory Board of Invest in ME Research and all the other volunteers and researchers working with them to establish diagnostic tests and medical treatment options for some 250,000 people with ME in UK and millions around the world.

Please click here to read the full update by Invest in ME Research, where you will also find info and links to the charity’s various other projects related to developing a UK Centre of Excellence for ME needing further funding, such as the Gut Microbiota Research, education for medical students and the charity’s international biomedical research conference events: http://www.investinme.org/ce-news-1708-01.shtml

We have reposted an extract below.

Well done everybody and thank you for your support!

Invest in ME Research has now reached the target set for the B-cell/rituximab fund.

This is another major target reached and is a wonderful achievement by dedicated supporters and friends across the world. The total of funds raised or pledged for B-cell/rituximab projects is £520,000.

From this the charity has already funded research at UCL, including a PhD student, and allowed strong collaboration to be formed with the researchers at Haukeland University Hospital in Bergen, Norway.

The initial preliminary B-cell study at UCL looked for likely responders and also introduced the UCL team to research into ME [1], leading to a UK rituximab trial.

This early work also created the foundations of close collaboration between the UK team and the Norwegian researchers at Haukeland University Hospital in Bergen.

This working collaboration and the work performed at UCL was credited as enormously valuable to the Norwegian rituimab trial work by one of the specialists there.

Once it became clear that a reorganisation at UCL would mean the UK trial could not take place there, and once it was decided that the trial could proceed at Norwich Research Park, then further collaboration was made and the Norwegian team visited Norwich in force in January 2017 to discuss with the UK team – UEA, IFR (now Quadram Institute Biosciences) and UCL – at the Centre there – click here.

As we now make preparations for the next phase, a new visit to Norwich is planned for when the Norwegian team break the codes for their Phase III trial later in 2017.

From the £520,000 raised Fane Mensah was also funded with a PhD grant to continue the B-cell research which is so important. This work was described here (click here).

Recently this work has been expanded thanks to a grant from Solve ME/CFS in USA which allowed Fane and Chris Armstrong to collaborate (click here).

Chris and Fane met when both were invited by IiMER to the sixth Biomedical Research into ME Colloquium (BRMEC6) in London in 2016. Dr Zaher Nahle from Solve was there also, and so another collaboration ensued. The work funded by IiMER has produced this paper from Fane and collaborators – Chronic fatigue syndrome and the immune system: Where are we now? [2]

Our initial target of £350,000 which was set with our advisor some years ago was reached and allowed the additional B-cell research to take place.

A position for a Senior Research Assistant to help with the UK trial is being advertised.

Our plans are to continue to raise funds for the UK Centre of Excellence for ME where international collaboration is a key concept.

We are pleased that Professor Ian Charles of Quadram Institute discussed the possibilities with the Centre in his keynote speech at the recent IIMEC12 International ME Conference in London (DVD available here). Professor Charles stated that he hoped “…they were being ambitious enough” for the Centre.

Our thanks to the wonderful supporters who are making it possible to apply high-quality science to looking for the cause(s) of this disease.

Our dedicated microsite for the UK rituximab trial and B-cell research has more details.

We are working on updating that site shortly and will include it in the Centre of Excellence microsite.

We will also be introducing a blog section which will allow the IiMER-funded researcher to interact more.

We hope to begin that soon – more details here.

Our mascot, Professor Let’s Do It for ME, was created by our supporters and indicates the B-cell/rituximab total – posters by LDIFME’s Jan Laverick.

Please help us by supporting our campaign for the
UK Centre of Excellence for ME.

Ways to help us are shown in the column at the right of our page.

References

1.
http://onlinelibrary.wiley.com/doi/10.1111/cei.12749/pdf
2. https://www.researchgate.net/publication/316080804_Chronic_fatigue_syndrome_and_the_immune_system_Where_are_we_now
3.
http://investinme.org/ce-news-1702-01.shtml

Read more here: http://www.investinme.org/ce-news-1708-01.shtml

Crowdfunding Update!

£700,00k

ME Awareness Month May 2017 marks the next milestone on our journey towards raising money for the specific biomedical studies of the Invest in ME Research Centre of Excellence for Myalgic Encephalomyelitis.

Huge thanks to each and every person (and pet) whose donations, sponsorship, and fundraising efforts for Invest in ME Research enabled the charity’s biomedical research programme to begin in 2013 and to proceed without delays.

We desperately need diagnostic tests and medical treatment options for this disease to be available in the UK, and we patients and families can see that the Invest in ME Research Centre of Excellence is on the fast-track to making this happen, but they cannot do it without your help.

Please keep the momentum going!

This is just a quick funding update so we plan to write more soon.

Invest in ME Research on Gut Microbiota in ME:
http://www.investinme.org/ce-news-1705-03.shtml

Invest in ME Research on B-cells/Rituximab Trial for ME:
http://www.investinme.org/ce-news-1705-02.shtml

Well done and thank you for your support!

Donate £1 to 1st Class ME Research

The original idea by Ruth Gilchrist for One Day – One Pound was for as many people as possible to donate just £1 on May 12th International ME Awareness Day to the charity Invest in ME Research to show support and help raise vital funds for 1st class biomedical research for tests and treatments for ME (Myalgic Encephalomyelitis).

We extended this to include a monthly reminder of our ongoing fundraising for this vital cause on the 1st of each month. Donations at any time are welcome. Every £1 makes a big difference to the vital work of this small charity – Invest in ME Research. View and share the excellent news report by BBC Look East to see just what a difference your donations make – www.bbc.co.uk/iplayer/episode/b08bbztq/look-east-late-news-26012017

The early evening news clip is also on youtube: www.youtube.com/watch?v=tF3jZWVc8F8&feature=youtu.be

Clip of the studio interview with Professor Simon Carding: www.youtube.com/watch?v=cSmxDmy-O8g

(more updates on the talks to follow, further to our January summary)

You can donate to the charity via JustGiving, PayPal, Bank Transfer, Cheque, or SMS. They are also registered with Big Give, and BT mydonate

Gift Aid is an extra 25% of your donation from the government if you are a UK tax-payer, so please tick the Gift Aid box when you donate if this applies to you.

WAYS TO DONATE

JustTextGiving (UK)

Text APFR99

£1-£5 or £10

to 70070

You can add your name and Gift Aid if eligible by text.

JustGiving
(any country, any amount from £2)

https://www.justgiving.com/onedayonepound/
(text donations add to the total raised on this page).

PayPal

To: paypal@investinme.org

Bank Transfer

Bank: Lloyds TSB Heartsease

Sorting code: 77-66-53

Account number: 22439568

Bank Transfer from outside the UK

IBAN: GB63 LOYD 77665322439568

BIC/SWIFT: LOYDGB21E05

Cheque

Send cheques payable to ‘Invest in ME Research’ to:

Invest in ME Research
PO Box 561,
Eastleigh,
Hampshire,
SO50 0GQ

(add Gift Aid to your donation with Invest in ME Research Gift Aid form)



Please help spread the word….

Let’s Do it for ME is a patient-driven campaign launched in 2011 in support of the proposal by independent UK charity Invest in ME Research to establish a centre of excellence for translational research and patient care based around Norwich Research Park in East Anglia; the first of its kind in UK/Europe and in collaboration with other leading UK and international biomedical researchers.

We help to raise funds for the biomedical research into myalgic encephalomyelitis that the charity is organising and/or funding in their development of the centre of excellence. Our crowdfunding for specific ME research is the first of its kind in UK and has inspired similar projects in Europe and USA. We have now helped to raise over £680,000 for the IiME Research strategy to develop and are aiming for £1,000,000.

The current focus of the research is on the role of the immune system, including infection and autoimmunity. Two major research projects are on the role of the gut microbiome and research on B-cells leading to a UK clinical treatment trial of rituximab.

Invest in ME Research is run entirely by volunteers who either have ME or are parents and carers of ME patients. They are driving the agenda of scientific research into diagnostic tests and treatments for myalgic encephalomyelitis in UK in collaboration with international researchers of world renown.

Thank you for your support.

Let’s Do It for ME!
ldifme.org

in support of Invest in ME Research
investinme.org

Invest in ME Research Centre of Excellence for ME
investinme.org/research-centre.shtml

Invest in ME International Conference & Biomedical Researchers Colloquium
investinme.eu

IIME B-cell / Rituximab Research
ukrituximabtrial.org

11th international IiME conference 2016 DVDs now available!

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The DVDs from the 11th international Invest in ME conference 2016 are now available to order via PayPal or postal cheque.  Starting at  £14 for Uk purchases, £15 Europe, £17 rest of the world, the DVDs show full presentations from conference plus pre-conference dinner speech. Click here to be the first to buy!

www.investinme.eu/IIMEC11.shtml#dvd

Registration for the 12th international Invest in ME Conference (#IIMEC12) 2nd June 2017 now open –
http://www.investinme.eu/IIMEC12.shtml#register